Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-N-(2-methoxy-phenyl)-benzenesulfonamide → N-cyclopropyl-3-(1-oxo-4-(thiophen-2-ylsulfonylimino)-1,4-dihydronaphthalen-2-ylthio)propanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(3-chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-N-(2-methoxy-phenyl)-benzenesulfonamide | HCID 44608656 | — |
| 반응물 | 4,5-dichloro-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide | HCID 67330668 | — |
| 반응물 | 3-mercapto-N-cyclopropylpropanamide | HCID 86656567 | — |
| 생성물 | N-cyclopropyl-3-(1-oxo-4-(thiophen-2-ylsulfonylimino)-1,4-dihydronaphthalen-2-ylthio)propanamide | HCID 67330263 | — |
반응 단계
5.2.43 N-cyclopropyl-3-(1-oxo-4-(thiophen-2-ylsulfonylimino)-1,4-dihydronaphthalen-2-ylthio)propanamide (13h) was prepared according to the procedure for 13d except using 4,5-dichloro-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)thiophenesulfonamide (12c) and 3-mercapto-N-cyclopropylpropanamide which afforded the title compound 20 mg (37%) as a yellow solid, m.p.: ° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08673910B2 |
| 출처 데이터셋 | uspto-grants-2014_03 |
| ORD ID | ord-e70cfc4352a9457d937cb9b8a5009772 |
| 출처 메모 | uspto-grants-2014_03 |