6-(Oxiran-2-yl)nicotinonitrile → 6-(1-Hydroxy-2-{4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin-1-yl}ethyl)pyridine-3-carbonitrile
반응식
[O:1]1[CH2:3][CH:2]1[C:4]1[N:9]=[CH:8][C:7]([C:10]#[N:11])=[CH:6][CH:5]=1.[OH:12][C@H:13]([C:21]1[CH:30]=[CH:29][C:24]2[C:25](=[O:28])[O:26][CH2:27][C:23]=2[C:22]=1[CH3:31])[CH2:14][N:15]1[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1>CCO>[OH:1][CH:2]([C:4]1[N:9]=[CH:8][C:7]([C:10]#[N:11])=[CH:6][CH:5]=1)[CH2:3][N:18]1[CH2:19][CH2:20][N:15]([CH2:14][C@H:13]([OH:12])[C:21]2[CH:30]=[CH:29][C:24]3[C:25](=[O:28])[O:26][CH2:27][C:23]=3[C:22]=2[CH3:31])[CH2:16][CH2:17]1참가 물질
4
반응물 2
생성물 1
시약·촉매·용매 1
반응 조건
- 온도
- 140 °C