N-tert-Butoxycarbonyl-L-aspartic acid beta-benzyl ester → HCID 66874810, 화합물

반응식

[ClH:1].Cl.[CH2:3]([O:10][C:11](=[O:19])[CH2:12][C@@H:13]([NH2:18])[CH2:14][N:15]([CH3:17])[CH3:16])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.C(OC(=O)C[C@@H](C(O)=O)NC(OC(C)(C)C)=O)C1C=CC=CC=1>>[ClH:1].[ClH:1].[CH2:3]([O:10][C:11](=[O:19])[CH2:12][C@H:13]([NH2:18])[CH2:14][N:15]([CH3:16])[CH3:17])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

반응물 2

HCID 1581888N-tert-Butoxycarbonyl-L-aspartic acid beta-benzyl ester

HCID 46223507(R)-benzyl 3-amino-4-(dimethylamino)butanoate dihydrochloride2회

생성물 1

HCID 66874810HCID 66874810, 화합물

실험 절차

(S)-3-Amino-4-dimethylamino-butyric acid benzyl ester dihydrochloride was prepared in analogy with (R)-3-amino-4-dimethylamino-butyric acid benzyl ester dihydrochloride (intermediate 1), starting from Boc-L-aspartic acid 4-benzyl ester.

출처 및 근거

ORD 기록: ord-eadca96b69bf47f5a123de8886b87a22
출처 데이터셋: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08673946B2

반응 노트

불러오는 중…