4-Methoxy-3-(trifluoromethyl)benzoyl chloride → 1-({5-[4-(Methyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
반응식
[C:1]([C:3]1[C:4]([C:17]([F:20])([F:19])[F:18])=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:12][C:13](=[NH:16])[NH:14][OH:15])[CH:7]=[CH:6]2)#[N:2].[CH3:21][O:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](Cl)=O)=[CH:25][C:24]=1[C:32]([F:35])([F:34])[F:33]>>[CH3:21][O:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]2[O:15][N:14]=[C:13]([CH2:12][N:8]3[C:9]4[C:5](=[C:4]([C:17]([F:19])([F:20])[F:18])[C:3]([C:1]#[N:2])=[CH:11][CH:10]=4)[CH:6]=[CH:7]3)[N:16]=2)=[CH:25][C:24]=1[C:32]([F:33])([F:35])[F:34]참가 물질
3
실험 절차
Synthesized as described in Example 70 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 4-(methyloxy)-3-(trifluoromethyl)benzoyl chloride. MS (ESI): m/z 467 (M+1).
후처리
- customSynthesized
출처 및 근거
- ORD 기록
- ord-c6f07896adcd4afaba2549b694251e69