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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1188545생성일: 2026년 10월 27일

3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → 2-Propyl-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-4,5-dicarbonitrile

https://huagongshe.com/reaction/1188545

반응식

참여 물질

역할이름HCID투입량
반응물3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazoleHCID 2736622—
반응물2-propyl-1H-indole-4,5-dicarbonitrileHCID 57800367—
생성물2-Propyl-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-4,5-dicarbonitrileHCID 57800240—

반응 단계

Synthesized as described in Example 4 from 2-propyl-1H-indole-4,5-dicarbonitrile and 3-(chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole: 1H NMR (400 MHz, DMSO-d6) δ 8.30 (d, J=7.6 Hz, 1H), 8.25 (s, 1H), 8.14 (s, 1H), 8.07 (d, J=7.6 Hz, 1H), 7.90-7.80 (m, 2H), 7.70 (d, J=8.4 Hz, 1H), 5.95 (s, 2H), 3.06 (t, 2H), 1.79-1.67 (m, 2H), 0.95 (t, J=7.2 Hz, 3H); MS (ES) m/z 436 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08673948B2
출처 데이터셋uspto-grants-2014_03
ORD IDord-34fe45259b4f406aa2f24c2b03f5bcb8
출처 메모uspto-grants-2014_03