돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1188652생성일: 2026년 10월 26일

3-(Trifluoromethyl)phenylboronic acid → 2-Methyl-4-(trifluoromethyl)-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-3-yl}methyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/1188652

반응식

참여 물질

역할이름HCID투입량
반응물3-(Trifluoromethyl)phenylboronic acidHCID 2734388—
반응물1-[(5-Chloro-1,2,4-thiadiazol-3-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405013—
생성물2-Methyl-4-(trifluoromethyl)-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-3-yl}methyl)-1H-indole-5-carbonitrileHCID 86620710—

반응 단계

Synthesized as described in Example 327 using 1-[(5-chloro-1,2,4-thiadiazol-3-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 326) and [3-(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 467 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08673948B2
출처 데이터셋uspto-grants-2014_03
ORD IDord-8d03d3be2ec84014818766c65b64ecee
출처 메모uspto-grants-2014_03