Nitrogen → HCID 86664910, 화합물

HRID 1189383노트

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HRID 1189383 반응식
N#N.[CH2:3]([C:5]1[O:6][C:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:8]([C:10](O)=[O:11])[N:9]=1)[CH3:4].CN(C=O)C.C(Cl)(=O)C([Cl:27])=O>C1(C)C=CC=CC=1>[CH2:3]([C:5]1[O:6][C:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:8]([C:10]([Cl:27])=[O:11])[N:9]=1)[CH3:4]

참가 물질

6

반응물 4

HCID 947NitrogenHCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 669290412-Ethyl-5-phenyl-oxazole-4-carboxylic acid

생성물 1

HCID 86664910HCID 86664910, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a suspension of 2-ethyl-5-phenyl-oxazole-4-carboxylic acid (54 mg, 0.25 mmol) in toluene (1.0 mL) was treated with a drop of DMF followed by oxalyl chloride (0.08 mL, 0.86 mmol) and the resulting yellow solution was stirred at rt for 30 min. The solvent was then removed under reduced pressure (coevaporation with toluene) to give 2-ethyl-5-phenyl-oxazole-4-carbonyl chloride.

후처리

  1. customThe solvent was then removed under reduced pressure (coevaporation with toluene)

출처 및 근거

ORD 기록
ord-05b66699d4c54163a17d1a96e04fa562
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08674111B2

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