Ammonia → 3-Amino-4-chloro-2-fluoro-benzamide

HRID 1189621노트

반응식

HRID 1189621 반응식
[NH2:1][C:2]1[C:3]([F:12])=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[C:5](O)=[O:6].ClC([N:18](C)C)=C(C)C.N>>[NH2:1][C:2]1[C:3]([F:12])=[C:4]([CH:8]=[CH:9][C:10]=1[Cl:11])[C:5]([NH2:18])=[O:6]

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 6407921-Chloro-N,N-2-trimethylpropenylamineHCID 667650743-Amino-4-chloro-2-fluorobenzoic acid

생성물 1

HCID 667651113-Amino-4-chloro-2-fluoro-benzamide수율 69%

실험 절차

The sub-title compound is prepared from 3-amino-4-chloro-2-fluoro-benzoic acid, (1-chloro-2-methyl-propenyl)-dimethyl-amine and conc NH3 in analogy to step Ac.

출처 및 근거

ORD 기록
ord-cfc75935c36044a2b862a1a3d0099ecc
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08674113B2

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