1-Ethyl-4-(4-nitrobenzyl)piperazine → 4-[(4-Ethylpiperazin-1-yl)methyl]aniline

HRID 1189743노트

반응식

HRID 1189743 반응식
[CH2:1]([N:3]1[CH2:8][CH2:7][N:6]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=2)[CH2:5][CH2:4]1)[CH3:2]>C(Cl)Cl.CO>[CH2:1]([N:3]1[CH2:8][CH2:7][N:6]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[CH:12][CH:11]=2)[CH2:5][CH2:4]1)[CH3:2]

참가 물질

3

반응물 1

HCID 7925571-Ethyl-4-(4-nitrobenzyl)piperazine

생성물 1

HCID 10849964-[(4-Ethylpiperazin-1-yl)methyl]aniline

시약·촉매·용매 1

HCID 21226129Dichloromethane methanol용매

실험 절차

The title compound was prepared in analogy to the procedure described in Step 11.1 but using 1-ethyl-4-(4-nitro-benzyl)-piperazine (Step 12.2): ESI-MS: 220.1 [M+H]+; TLC: Rf=0.08 (DCM/MeOH+1% NH3aq, 9:1).

출처 및 근거

ORD 기록
ord-2e7993b87d4d4d1e974842f7089900ab
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08674099B2

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