Ammonia → 4-Ethyl-7-(4-nitro-phenylazo)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

HRID 1190779노트

반응식

HRID 1190779 반응식
F[B-](F)(F)F.[N+:6]([C:9]1[CH:14]=[CH:13][C:12]([N+:15]#[N:16])=[CH:11][CH:10]=1)([O-:8])=[O:7].[CH2:17]([N:19]1[C:24]2[CH:25]=[C:26]([OH:29])[CH:27]=[CH:28][C:23]=2[O:22][CH2:21][CH2:20]1)[CH3:18].N>S(=O)(=O)(O)O>[CH2:17]([N:19]1[C:24]2[CH:25]=[C:26]([OH:29])[C:27]([N:16]=[N:15][C:12]3[CH:11]=[CH:10][C:9]([N+:6]([O-:8])=[O:7])=[CH:14][CH:13]=3)=[CH:28][C:23]=2[O:22][CH2:21][CH2:20]1)[CH3:18]

참가 물질

5

반응물 3

HCID 222AmmoniaHCID 680064-Nitrobenzenediazonium tetrafluoroborateHCID 687776134-Ethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

생성물 1

HCID 1363315334-Ethyl-7-(4-nitro-phenylazo)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

p-Nitrobenzenediazonium tetrafluoroborate (0.251 g, 1.06 mmol) was dissolved in 10% sulfuric acid (10 ml) and added to a methanolic solution (10 ml) of 50a (0.19 g, 1.06 mmol). The solution turned red immediately. The reaction mixture was neutralized with ammonia. The red precipitate was filtered to give quantitative yield of the product. ES-HRMS [M−H]− 327.1428. Calcd for (C16H15N4O4): 327.1094.

후처리

  1. filtrationThe red precipitate was filtered

출처 및 근거

ORD 기록
ord-3f8f00a583894ec9a8897db4f9fb689d
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08679776B2

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