Ammonium Hydroxide → Benzenesulfonamide, 2-(4-isoxazolyl)-
반응식
[O:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[S:12](Cl)(=[O:14])=[O:13])[CH:3]=[N:2]1.[OH-].[NH4+:17]>O1CCCC1>[O:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[S:12]([NH2:17])(=[O:14])=[O:13])[CH:3]=[N:2]1참가 물질
4
실험 절차
By the procedure of Example 5, 15 g of 2-(isoxazol-4-yl)benzenesulfonyl chloride prepared in Example 12 was reacted with 30 ml of concentrated ammonium hydroxide in 150 ml of tetrahydrofuran to give, after recrystallization from 2-propanol, 11 g of the title compound; m.p. 165°-167° C.
후처리
- customto give
- customafter recrystallization from 2-propanol, 11 g of the title compound
출처 및 근거
- ORD 기록
- ord-dabe02416c484bfd942fd80b0b4abd88
- 출처 데이터셋
- uspto-grants-1989_03
- 특허 번호
- US04810282
반응 노트
불러오는 중…