Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lactic Acid → 2-((6-Chrysenylmethyl)amino)-2-methyl-1,3-propanediol lactate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lactic Acid | HCID 612 | — |
| 반응물 | Crisnatol | HCID 57062 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-((6-Chrysenylmethyl)amino)-2-methyl-1,3-propanediol lactate | HCID 54537940 | 44.1% |
반응 단계
A mixture of 2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol free base (1D) (3.45 g, 10 mmol) and lactic acid (Fisher Scientific Co., 711 Forbes Ave., Pittsburgh, PA, 15219, 85% liquid, 1.04 g, 10 mmol) in CH3OH (500 mL) was brought to reflux and filtered through a glass fritted funnel. The solvent was removed by rotary evaporation to give a crude white solid. This was crystallized (CH3OH/Et2O) 3x to give 1.84 g (42.2%) of 2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol lactate mp 163°-164°. (C,H,N).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04810727 |
| 출처 데이터셋 | uspto-grants-1989_03 |
| ORD ID | ord-d10b57afb1664530a58aa066a9f4f298 |
| 출처 메모 | uspto-grants-1989_03 |