Sulfuric Acid → HCID 21270719, 화합물

반응식

[Br:1][C:2]1[C:7]([O:8]C(C)C)=[CH:6][C:5]([N:12]2[C:17](=[O:18])[CH:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[N:14]=[C:13]2[O:23][CH3:24])=[C:4]([F:25])[CH:3]=1.S(=O)(=O)(O)O>>[Br:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([N:12]2[C:17](=[O:18])[CH:16]=[C:15]([C:19]([F:20])([F:22])[F:21])[N:14]=[C:13]2[O:23][CH3:24])=[C:4]([F:25])[CH:3]=1

참가 물질

반응물 2

HCID 1118Sulfuric Acid

HCID 21270714HCID 21270714, 화합물

생성물 1

HCID 21270719HCID 21270719, 화합물

실험 절차

using 1-(4-bromo-2-fluoro-5-isopropoxyphenyl)-2-methoxy-4-trifluoromethyl-6(1H)-pyrimidinone with concentrated sulphuric acid there is obtained 1-(4-bromo-2-fluoro-5-hydroxyphenyl)-2-methoxy-4-trifluoromethyl-6(1H)-pyrimidinone, m.p. 132°-136° C.;

출처 및 근거

ORD 기록: ord-dc80509a9af24d79ad19b1d25d50d99f
출처 데이터셋: uspto-grants-1989_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04812164

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