참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Furan | HCID 8029 | — |
| 반응물 | Heptanoic Acid | HCID 8094 | — |
| 반응물 | Acetic acid, 2,2-dichloro-, 1,1'-anhydride | HCID 77772 | — |
| 반응물 | Boron | HCID 5462311 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Heptanoylfuran | HCID 231327 | 99.3% |
반응 단계
In 50 ml of toluene were dissolved 6.51 g (0.05 mole) of heptanoic acid, 4.43 g (0.065 mole) of furan and 14.39 g (0.06 mole) of dichloroacetic anhydride. To the resulting solution was added 0.71 g of boron trifluoridediethyl ether coplex and the resulting mixture was then stirred at 50° C. for 3 hours. After completion of the reaction, the reaction solution was cooled and washed successively with 5% aqueous sodium carbonate solution and water. The organic layer was concentrated under reduced pressure and the resulting concentrated residue was then purified by silica gel-filled column chromatography to obtain 8.95 g of 2-heptanoylfuran.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04812585 |
|---|
| 출처 데이터셋 | uspto-grants-1989_03 |
|---|
| ORD ID | ord-218971747ed74ae7872997c922fec91f |
|---|
| 출처 메모 | uspto-grants-1989_03 |
|---|
