Anisole → HCID 178503585, 화합물

HRID 1194297노트

반응식

HRID 1194297 반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](=[CH:12][CH:13]=1)[N:7]=[C:8]([S:10][CH3:11])[N:9]=2.[C:14]1(OC)C=CC=CC=1.[F:22][C:23]([F:30])([F:29])[S:24]([O:27]C)(=[O:26])=[O:25]>C(OCC)(=O)C>[F:22][C:23]([F:30])([F:29])[S:24]([O-:27])(=[O:26])=[O:25].[CH3:14][N:9]1[C:5]2=[CH:4][CH:3]=[C:2]([CH3:1])[CH:13]=[CH:12][C:6]2=[NH+:7][CH:8]1[S:10][CH3:11]

참가 물질

5

반응물 3

HCID 7519AnisoleHCID 9526Methyl triflateHCID 200643756-Methyl-2-(methylsulfanyl)cyclohepta[d]imidazole

생성물 1

HCID 178503585HCID 178503585, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

6-Methyl-2-methylthiocycloheptimidazole (27 g) was added to 100 ml of anisole and stirred under ice cooling. Then, 28 g of methyl trifluoromethanesulfonate was added dropwise thereto, and stirred under ice cooling. The mixture was further stirred at room temperature for one hour, 200 ml of ethyl acetate was added, and deposited crystals were collected by filtration and dried.

후처리

  1. stirringstirred under ice cooling
  2. stirringThe mixture was further stirred at room temperature for one hour
  3. filtrationwere collected by filtration
  4. customdried

출처 및 근거

ORD 기록
ord-75cb94b97c944c6da485b398bf71388d
출처 데이터셋
uspto-grants-1989_03
특허 번호
US04814265

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