1-(triphenylmethyl)-1H-imidazole-4-carbaldehyde → HCID 14520344, 화합물

HRID 1194370

반응식

HRID 1194370 반응식
Br[C:2]1[CH:11]=[CH:10][C:5]2[O:6][CH2:7][O:8][CH2:9][C:4]=2[CH:3]=1.[C:12]1([C:18]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:19]2[CH:23]=[C:22]([CH:24]=[O:25])[N:21]=[CH:20]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[O:6]1[C:5]2[CH:10]=[CH:11][C:2]([CH:24]([C:22]3[N:21]=[CH:20][N:19]([C:18]([C:12]4[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=4)([C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=4)[C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH:23]=3)[OH:25])=[CH:3][C:4]=2[CH2:9][O:8][CH2:7]1

참가 물질

3

반응물 2

HCID 6182331-(triphenylmethyl)-1H-imidazole-4-carbaldehydeHCID 145203376-Bromo-4H-1,3-benzodioxine

생성물 1

HCID 14520344HCID 14520344, 화합물수율 53%

실험 절차

This compound is prepared like the preceding compound but starting from 6-bromo-4H-1,3-benzodioxin and 1-triphenylmethyl-1H-imidazole-4-carboxaldehyde. After decomposing the reaction mixture, the reaction product is extracted with dichloromethane and recrystallized from isopropyl alcohol. By chromatography of the residue obtained after evaporation of the mother liquors, there is obtained a second crop of product. Yield: 53% of theory; M.P.: 165°-167° C.

후처리

  1. customThis compound is prepared like the preceding compound
  2. extractionthe reaction product is extracted with dichloromethane
  3. customrecrystallized from isopropyl alcohol
  4. customBy chromatography of the residue obtained
  5. customafter evaporation of the mother liquors
  6. customthere is obtained a second crop of product

출처 및 근거

ORD 기록
ord-8522ab1a0ab442ca861b3c58720b5f57
출처 데이터셋
uspto-grants-1989_03
특허 번호
US04814343

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