참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | (2,3-Dihydroxypropyl)trimethylammonium chloride | HCID 161796 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (3-Chloro-2-hydroxypropyl)trimethylammonium chloride | HCID 18732 | 96.6% |
반응 단계
There was suspended 9.20 g of 2,3-dihydroxypropyltrimethylammonium chloride (chemical purity: 100%) in 50 ml of dimethylformamide, and thereto 6.80 g of thionyl chloride was added at a temperature from 5° to 10° C. After stirring for 20 minutes, it was heated at 100° C. for 5 hours. Finally, after cooling the reaction mixture to room temperature, 9.85 g of 3-chloro-2-hydroxypropyltrimethylammonium chloride was obtained by evaporating the reaction mixture to dryness.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04814506 |
|---|
| 출처 데이터셋 | uspto-grants-1989_03 |
|---|
| ORD ID | ord-238c38f59d2e443fb190bf3a294c551d |
|---|
| 출처 메모 | uspto-grants-1989_03 |
|---|
