Bromocyclopentane → ethyl (2Z)-2-cyclopentyloxyimino-3-oxobutanoate

반응식

[OH:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5].[CH:12]1(Br)[CH2:16][CH2:15][CH2:14][CH2:13]1>>[CH:12]1([O:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH2:16][CH2:15][CH2:14][CH2:13]1

참가 물질

반응물 2

HCID 8728Bromocyclopentane

HCID 178472876HCID 178472876, 화합물

생성물 1

HCID 14864952ethyl (2Z)-2-cyclopentyloxyimino-3-oxobutanoate수율 80%

실험 절차

Ethyl (Z)-2-(hydroxyimino)-3-oxobutyrate (7.9 g) was treated with cyclopentyl bromide as described in Example 4a, Method 2, except that the reaction was stirred overnight to give the title compound as a colourless liquid (9.Og, 80%), (Found: M+ +H, 228.1241. C11H17NO4 requires M+H, 228.1236); νmax (film) 2960 1745, 1700 cm-1 ; δH (CDCl3) 1.30 (3H, t), 1.6-2.0 (8H, m), 2.37 (3H, s), 4.31 (2H, q),and 4.87 (1H, m).

출처 및 근거

ORD 기록: ord-6b9cb141c450485b99498dc72045c12b
출처 데이터셋: uspto-grants-1989_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04816452

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