Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,3,3-Trifluoropropanal → (4R,9aR)-4-Methyl-6-((RS)-3,3,3-trifluoro-1-hydroxy-propyl)-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,3,3-Trifluoropropanal | HCID 68028 | — |
| 반응물 | (4R,9aR)-6-(2-hydroxy-ethoxymethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester | HCID 69557393 | — |
| 반응물 | HCID 178418306 | HCID 178418306 | — |
| 생성물 | (4R,9aR)-4-Methyl-6-((RS)-3,3,3-trifluoro-1-hydroxy-propyl)-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester | HCID 69556370 | — |
반응 단계
This compound was prepared in analogy to Example 38 intermediate, from (4R,9aR)-6-bromo-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester (Example 5, intermediate b), tert-butyllithium and 3,3,3-trifluoropropanal.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098337B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-e32ff7f058cb4325997af10b7ac9c6ab |
| 출처 메모 | uspto-grants-2006_08 |