p-Toluenesulfonic acid → HCID 19896184, 화합물

HRID 1196746노트

반응식

HRID 1196746 반응식
O.[O:2]=[CH:3][C:4]([Cl:7])([Cl:6])[Cl:5].[CH2:8]([OH:13])[CH2:9][CH:10]([CH3:12])[CH3:11].[CH3:14][C:15]1[CH:20]=CC(S(O)(=O)=O)=[CH:17][CH:16]=1>C1C=CC=CC=1>[CH2:17]([O:2][CH:3]([O:13][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])[C:4]([Cl:7])([Cl:6])[Cl:5])[CH2:16][CH:15]([CH3:20])[CH3:14]

참가 물질

5

반응물 3

HCID 6101p-Toluenesulfonic acidHCID 31260Isoamyl AlcoholHCID 205283762,2,2-Trichloroacetaldehyde hydrate

생성물 1

HCID 19896184HCID 19896184, 화합물

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

A mixture of 5 g of chloral-hydrate, 10 g of isoamyl-alcohol, 0.1 g of 4-methyl-benzene-sulphonic acid and 50 ml of benzene is kept at reflux temperature and the formed water is separated by means of a Dean-Stark apparatus. After a reaction time of 9 hours the benzene is washed with a sodium-hydrogen-carbonate solution and water, dried on magnesium sulfate, then vacuum distilled.

후처리

  1. temperatureat reflux temperature
  2. customthe formed water is separated by means of a Dean-Stark apparatus
  3. washAfter a reaction time of 9 hours the benzene is washed with a sodium-hydrogen-carbonate solution and water
  4. customdried on magnesium sulfate
  5. distillationvacuum distilled

출처 및 근거

ORD 기록
ord-85812d933c214b1b86bac748c720cff6
출처 데이터셋
uspto-grants-1992_05
특허 번호
US05116402

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