Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-acetyl-L-methionine → 21-[2-(Acetylamino)-4-methylthio-1-oxobutylthio]-9-fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-acetyl-L-methionine | HCID 448580 | — |
| 반응물 | HCID 131717396 | HCID 131717396 | — |
| 생성물 | 21-[2-(Acetylamino)-4-methylthio-1-oxobutylthio]-9-fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione | HCID 88494358 | 53.4% |
반응 단계
The title compound (0.38 gm) was prepared from 9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione-21-thiol (0.50 gm) and N-acetyl-L-methionine (0.70 gm) in the same manner as in Synthetic Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05116829 |
| 출처 데이터셋 | uspto-grants-1992_05 |
| ORD ID | ord-2f89926fca1d4e44a5c3e2e4e431581b |
| 출처 메모 | uspto-grants-1992_05 |