Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Cysteine, N-acetyl-S-ethyl- → 21-[2-(Acetylamino)-3-etylthio-1-oxopropylthio]-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Cysteine, N-acetyl-S-ethyl- | HCID 147382 | — |
| 반응물 | 9-Fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-21-thiol | HCID 131717402 | — |
| 생성물 | 21-[2-(Acetylamino)-3-etylthio-1-oxopropylthio]-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione | HCID 88395374 | 29.5% |
반응 단계
The title compound (0.21 gm) was prepared from 9-fluoro-11 ,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione-21-thiol (0.5 gm) and N-acetyl-S-ethylcysteine (0.70 gm) in the same manner as in Synthetic Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05116829 |
| 출처 데이터셋 | uspto-grants-1992_05 |
| ORD ID | ord-8cb11f885d7e46b78341dadba13e2a42 |
| 출처 메모 | uspto-grants-1992_05 |