Acetaldehyde → N-[1-(2-thienyl)ethyl]-4-isopropylbenzamide

HRID 1197149노트

반응식

HRID 1197149 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH:6](=O)[CH3:7].[CH:9]([C:12]1[CH:20]=[CH:19][C:15]([C:16]([NH2:18])=[O:17])=[CH:14][CH:13]=1)([CH3:11])[CH3:10].C(O)=O.P(=O)(O)(O)O>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]([NH:18][C:16](=[O:17])[C:15]1[CH:19]=[CH:20][C:12]([CH:9]([CH3:11])[CH3:10])=[CH:13][CH:14]=1)[CH3:7]

참가 물질

5

반응물 4

HCID 177AcetaldehydeHCID 8030ThiopheneHCID 69277Benzamide, 4-(1-methylethyl)-HCID 21569781Formic acid phosphoric acid

생성물 1

HCID 14127108N-[1-(2-thienyl)ethyl]-4-isopropylbenzamide

실험 절차

Thiophene (100 mmol), acetaldehyde (10 mmol) and 4-isopropylbenzamide (10 mmol) were stirred in the following formic acid/phosphoric acid mixture at 20° C. for two hours to obtain N-[1-(2-thienyl)ethyl]-4-isopropylbenzamide:

출처 및 근거

ORD 기록
ord-5da666c35ecc4fc0ab6cf12476bfac6f
출처 데이터셋
uspto-grants-1992_05
특허 번호
US05117000

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