Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-Hexanedione → Ethyl 5,8-dimethylcarbazole-4-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-Hexanedione | HCID 8035 | — |
| 반응물 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 반응물 | Ethyl indole-4-carboxylate | HCID 605034 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Ethyl 5,8-dimethylcarbazole-4-carboxylate | HCID 19897884 | 39.8% |
반응 단계
A mixture of 13.24 g of ethyl indole-4-carboxylate, 15.98 g of acetonylacetone and 13.31 g of p-toluenesulfonic acid monohydrate in 50 ml of ethanol was refluxed for 10 hours. The ethanol was evaporated under reduced pressure, the residue was chromatographed on silica gel column with hexane - ethyl acetate (9 : 1) to give 7.45 g of ethyl 5,8-dimethylcarbazole-4-carboxylate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05116995 |
| 출처 데이터셋 | uspto-grants-1992_05 |
| ORD ID | ord-7011647797124f60ab76be0535658e02 |
| 출처 메모 | uspto-grants-1992_05 |