Acetic Acid → HCID 14674517, 화합물

HRID 1197233노트

반응식

HRID 1197233 반응식
[CH2:1]1[CH2:36][O:35][C:3]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])([CH2:4][CH2:5][C:6]23[CH2:13][CH:12]([O:14][C:15](=[O:28])[C:16]4C=CC(C5C=CC=CC=5)=CC=4)[CH2:11][CH:10]2CC(=O)O3)[O:2]1.C(=O)([O-])[O-:38].[K+].[K+].C(O)(=O)C>CO>[CH2:36]1[CH2:1][O:2][C:3]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])([CH2:4][CH2:5][C@H:6]2[C@H:10]([OH:38])[CH2:11][C@H:12]3[C@@H:13]2[CH2:16][C:15](=[O:28])[O:14]3)[O:35]1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 11430Potassium CarbonateHCID 867458653,3-Ethylenedioxyoctyl-7-(4-phenylbenzoyloxy)-2-oxabicyclo[3.3.0]octan-3-one

생성물 1

HCID 14674517HCID 14674517, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of (1S,5R,6R,7R)-6-(3,3-ethylenedioxyoctyl-7-(4-phenylbenzoyloxy)-2-oxabicyclo[3.3.0]octan-3-one (5a) (8.20 g) in methanol (200 ml) was added potassium carbonate (1.15 g) and the resultant mixture was stirred overnight, and acetic acid (lml) was added thereto. The crude product obtained by treating in the conventional manner was subjected to silica gel column chromatography to give the title compound (6a). Yield: 4.70 g (90.0%)

후처리

  1. customThe crude product obtained
  2. additionby treating in the conventional manner

출처 및 근거

ORD 기록
ord-f69056a96f6944fc9ef61349d5108cd4
출처 데이터셋
uspto-grants-1992_05
특허 번호
US05117042

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