Pyridine → Gla-aht
반응식
[CH3:1][C:2]1[C:15](=[O:16])[N:14]=[C:13]2[N:4]([C@@H:5]3[O:9][C@H:8]([CH2:10][OH:11])[C@H:7]([O:12]2)[CH2:6]3)[CH:3]=1.N1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:18][CH2:19][CH2:20][CH2:21][CH2:22]/[CH:22]=[CH:21]\[CH2:20]/[CH:19]=[CH:18]\[CH2:22]/[CH:21]=[CH:20]\[CH2:19][CH2:18][CH2:6][CH2:7][C:8]([O:11][CH2:10][CH:8]1[O:9][CH:5]2[N:4]3[C:13]([O:12][CH:7]1[CH2:6]2)=[N:14][C:15](=[O:16])[C:2]([CH3:1])=[CH:3]3)=[O:9]참가 물질
3
실험 절차
Anhydrothymidine (0.520 g, 2.319 mmol, as a dry white powder) was dissolved in anhydrous pyridine (10 ml) under an atmosphere of dry nitrogen, and to this stirred solution at room temperature was added GLA acid chloride (0.900 g, 3.02 mmol). Stirring was continued overnight after which period, TLC indicated complete loss of the starting material. The pyridine was
출처 및 근거
- ORD 기록
- ord-f4b0413425a043e68a1a6429d3d68dea
- 출처 데이터셋
- uspto-grants-1994_01