Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → N-[2-(5-methoxyindol-3-yl)ethyl]-N'-propylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 5-Methoxytryptamine | HCID 1833 | — |
| 반응물 | Propyl isocyanate | HCID 61033 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | N-[2-(5-methoxyindol-3-yl)ethyl]-N'-propylurea | HCID 10039072 | 85% |
반응 단계
0.851 g of propyl isocyanate is added to a suspension of 1.902 g of 5-methoxytryptamine in 4 cm3 of pyridine at +5° C. The mixture is stirred at room temperature for 2 hours and then the reaction medium is poured onto ice-water. The mixture is acidified slightly with a 1N hydrochloric acid solution. The resulting precipitate is isolated by filtration, washed with water, dried and then recrystallised in toluene, yielding 2.34 g (85%) of N-[2-(5-methoxyindol-3-yl)ethyl]-N'-propylurea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05276051 |
| 출처 데이터셋 | uspto-grants-1994_01 |
| ORD ID | ord-88b52ab1c006479a9be68752022de383 |
| 출처 메모 | uspto-grants-1994_01 |