Acetyl-beta-alanine tert-butyl ester → N-Acetyl-beta-alanine

HRID 1198500

반응식

HRID 1198500 반응식
C([O:5][C:6](=[O:13])[CH2:7][CH2:8][NH:9][C:10](=[O:12])[CH3:11])(C)(C)C.C(O)C.O.[NH4+].[OH-]>>[C:10]([NH:9][CH2:8][CH2:7][C:6]([OH:13])=[O:5])(=[O:12])[CH3:11]

참가 물질

3

반응물 2

HCID 19102537Acetyl-beta-alanine tert-butyl esterHCID 86596525Ethanol ammonium hydroxide water

생성물 1

HCID 76406N-Acetyl-beta-alanine수율 116.4%

실험 절차

Utilizing the procedure for converting 40a to 41a, 127 (0.10 g, 0.19 mmol) gave 128 (29 mg, 39%) as a fluffy solid after flash chromotography (silica, 10:1.2:1.2 ethanol/H2O/NH4OH).

출처 및 근거

ORD 기록
ord-5c03653d43c04599bcc91a5a20e574d6
출처 데이터셋
uspto-grants-1994_01
특허 번호
US05281585

연결된 노트

불러오는 중…