2,4'-Difluorobenzophenone → 1-Fluoro-2-[1-(4-fluorophenyl)ethenyl]benzene

반응식

Cl[C:2]1C=CC=CC=1C(C1C=CC(F)=CC=1)=O.[F:17][C:18]1[CH:32]=[CH:31][CH:30]=[CH:29][C:19]=1[C:20]([C:22]1[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=1)=O>>[F:17][C:18]1[CH:32]=[CH:31][CH:30]=[CH:29][C:19]=1[C:20]([C:22]1[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=1)=[CH2:2]

참가 물질

반응물 2

HCID 676512,4'-Difluorobenzophenone

HCID 745472-Chloro-4'-fluorobenzophenone

생성물 1

HCID 132357851-Fluoro-2-[1-(4-fluorophenyl)ethenyl]benzene수율 85%

실험 절차

The procedure described in Example 1 is repeated except that the 130 parts of 2-chloro-4'-fluorobenzophenone are replaced by 168 parts of 2,4'-difluorobenzophenone, which was converted into the title compound in 85% yield. Distillation, under vacuum, gives a colourless liquid which is pure 1-(2-fluorophenyl)-1-(4-fluorophenyl)ethene (b.pt. 82°/0.2 mm Hg).

출처 및 근거

ORD 기록: ord-271d830e2b8147e4bbd9ca317551027c
출처 데이터셋: uspto-grants-1990_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04898997

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