Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 1-(3,5-Dichlorophenyl)-4-methoxycarbonyl-5-pyrazolecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 1H-Pyrazole-4-carboxylic acid, 5-(aminocarbonyl)-1-(3,5-dichlorophenyl)- | HCID 163896 | — |
| 생성물 | 1-(3,5-Dichlorophenyl)-4-methoxycarbonyl-5-pyrazolecarboxamide | HCID 14421313 | — |
반응 단계
A 1.5 g portion of the compound of Example 2 was suspended in 30 ml of methanol, and hydrogen chloride gas was bubbled through the suspension for 1 minute. Then 30 ml of methanol was added over a 5 minute period while the addition of gas was continued. Then the mixture was heated under reflux for 2 hours, and was cooled and filtered. The solids were collected and dried to obtain 1.15 g of the desired product, m.p. 220°-222°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04902808 |
| 출처 데이터셋 | uspto-grants-1990_02 |
| ORD ID | ord-ebb6372c25844c07b7b346a7421e5219 |
| 출처 메모 | uspto-grants-1990_02 |