Acetic Acid → 2-Methoxy-4-(methylamino)-5-nitrophenol

HRID 1199872노트

반응식

HRID 1199872 반응식
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]2[O:9][CH2:10][O:11][C:6]2=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].C[O-].[Na+].C(O)(=O)C>CO.O>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([NH:2][CH3:1])[C:4]([N+:12]([O-:14])=[O:13])=[CH:5][C:6]=1[OH:11]

참가 물질

6

반응물 3

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13742671N-methyl-6-nitro-1,3-dioxaindan-5-amine

생성물 1

HCID 137426772-Methoxy-4-(methylamino)-5-nitrophenol

시약·촉매·용매 2

HCID 887Methanol용매2회HCID 962Water용매

실험 절차

A solution of 0.1 mol (19.6 g) of 2-methylamino-4,5-methylenedioxy-1-nitrobenzene, prepared according to Example 3, in 80 ml of a 30% strength solution of sodium methylate in methanol is brought for 15 minutes to the refluxing temperature of the methanol. The reaction medium is diluted with 500 ml of water. After the filtrate has been neutralized with acetic acid, the expected product precipitates.

후처리

  1. customthe expected product precipitates

출처 및 근거

ORD 기록
ord-fd2a6e379c2741a8adff488735ab62ea
출처 데이터셋
uspto-grants-1990_02
특허 번호
US04904276

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