4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrimidin-2-amine → Pyridine-3-sulfonic acid [5-(2-amino-4-methyl-pyrimidin-5-yl)-2-chlorophenyl]-amide

반응식

[Br:18][c:19]1[cH:20][cH:21][c:22]([Cl:35])[c:23]([NH:25][S:26](=[O:27])(=[O:28])[c:29]2[cH:30][n:31][cH:32][cH:33][cH:34]2)[cH:24]1.[CH3:1][c:2]1[n:3][c:4]([NH2:17])[n:5][cH:6][c:7]1[B:8]1[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]1>>[CH3:1][c:2]1[n:3][c:4]([NH2:17])[n:5][cH:6][c:7]1-[c:19]1[cH:20][cH:21][c:22]([Cl:35])[c:23]([NH:25][S:26](=[O:27])(=[O:28])[c:29]2[cH:30][n:31][cH:32][cH:33][cH:34]2)[cH:24]1

참가 물질

반응물 2

HCID 529879064-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrimidin-2-amine

HCID 62907758Pyridine-3-sulfonic acid [5-bromo-2-chloro-phenyl]-amide

생성물 1

HCID 86761609Pyridine-3-sulfonic acid [5-(2-amino-4-methyl-pyrimidin-5-yl)-2-chlorophenyl]-amide

출처 및 근거

ORD 기록: ord-47d2408d64a74f0a961d8b66f1ff1dcf
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

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