Ketamine → Testosterone

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Male AR-97Q mice and their normal littermates were castrated or sham-operated via the abdominal route under ketamine-xylazine anesthesia (50 mg/kg ketamine and 10 mg/kg xylazine, i.p.) at 4 weeks of age. Female AR-97Q mice and their littermates were subcutaneously injected 20 μg of testosterone enanthate dissolved in 20 μl of sesame oil weekly from 4 weeks of age until the end of the analysis. The control mice were given the same amount of sesame oil.

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