Acetonitrile → N-[2-(t-butylamino)-5-chloro-3,6-difluoropyridin-4-yl]phthalimide

반응식

[C:22]([CH3:23])([CH3:24])([CH3:25])[NH2:26].[CH3:27][C:28]#[N:29].[Cl:1][c:2]1[c:3]([F:21])[n:4][c:5]([F:20])[c:6]([F:19])[c:7]1[N:8]1[C:9](=[O:18])[c:10]2[c:11]([cH:14][cH:15][cH:16][cH:17]2)[C:12]1=[O:13]>>[Cl:1][c:2]1[c:3]([F:21])[n:4][c:5]([NH:26][C:22]([CH3:23])([CH3:24])[CH3:25])[c:6]([F:19])[c:7]1[N:8]1[C:9](=[O:18])[c:10]2[c:11]([cH:14][cH:15][cH:16][cH:17]2)[C:12]1=[O:13]

참가 물질

반응물 3

HCID 6342Acetonitrile

HCID 6385Tert-Butylamine

HCID 221212012-(3-Chloro-2,5,6-trifluoropyridin-4-yl)-1H-isoindole-1,3(2H)-dione

생성물 1

HCID 22121242N-[2-(t-butylamino)-5-chloro-3,6-difluoropyridin-4-yl]phthalimide

출처 및 근거

ORD 기록: ord-5faf9f709b09498cb4c351e287821e71
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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