Tetrahydrofuran → 1,1-Dimethylethyl 4-(3-{6-[(2,2-dimethylpropanoyl)amino]-2-fluoro-3-pyridinyl}-3-hydroxypropyl)-1-piperidinecarboxylate

HRID 1205693노트

반응식

HRID 1205693 반응식
[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[n:7]1.[O:15]=[CH:16][CH2:17][CH2:18][CH:19]1[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]1.[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[F:1][c:2]1[c:3]([CH:16]([OH:15])[CH2:17][CH2:18][CH:19]2[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]2)[cH:4][cH:5][c:6]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[n:7]1

참가 물질

4

반응물 3

HCID 8028TetrahydrofuranHCID 10657745Tert-butyl 4-(3-oxopropyl)piperidine-1-carboxylateHCID 131542516-Fluoro-2-pivaloylaminopyridine

생성물 1

HCID 222626141,1-Dimethylethyl 4-(3-{6-[(2,2-dimethylpropanoyl)amino]-2-fluoro-3-pyridinyl}-3-hydroxypropyl)-1-piperidinecarboxylate

출처 및 근거

ORD 기록
ord-4cc64a9d6f45427c8f3addf49da6b170
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

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