Pyridine → 4-(2-methanesulfonylamino-1H-benzimidazol-4-yl)carbonylamino-3-methoxy-N-methyl-N-[4-methyl-2-[5-(4-methylpiperazin-1-yl)carbonylpent-1-yloxy]phenyl]benzamide

반응식

[CH3:48][S:49]([Cl:50])(=[O:51])=[O:52].[NH2:1][c:2]1[n:3][c:4]2[c:5]([nH:6]1)[cH:7][cH:8][cH:9][c:10]2[C:11](=[O:12])[NH:13][c:14]1[c:15]([O:46][CH3:47])[cH:16][c:17]([C:18](=[O:19])[N:20]([c:21]2[c:22]([O:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][C:34](=[O:35])[N:36]3[CH2:37][CH2:38][N:39]([CH3:42])[CH2:40][CH2:41]3)[cH:23][c:24]([CH3:27])[cH:25][cH:26]2)[CH3:43])[cH:44][cH:45]1.[cH:53]1[cH:54][cH:55][n:56][cH:57][cH:58]1>>[NH:1]([c:2]1[n:3][c:4]2[c:5]([nH:6]1)[cH:7][cH:8][cH:9][c:10]2[C:11](=[O:12])[NH:13][c:14]1[c:15]([O:46][CH3:47])[cH:16][c:17]([C:18](=[O:19])[N:20]([c:21]2[c:22]([O:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][C:34](=[O:35])[N:36]3[CH2:37][CH2:38][N:39]([CH3:42])[CH2:40][CH2:41]3)[cH:23][c:24]([CH3:27])[cH:25][cH:26]2)[CH3:43])[cH:44][cH:45]1)[S:49]([CH3:48])(=[O:51])=[O:52]