Amidinothiourea → HCID 178451655, 화합물

HRID 12060

반응식

HRID 12060 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH:10](Br)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[C:16]([NH2:22])([NH2:21])=[N:17][C:18]([NH2:20])=[S:19]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11]2[N:20]=[C:18]([NH:17][C:16]([NH2:22])=[NH:21])[S:19][C:10]=2[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 2724563AmidinothioureaHCID 106839701-tert-Butyloxycarbonyl-3-bromo-4-oxopiperidine

생성물 1

HCID 178451655HCID 178451655, 화합물

실험 절차

Analogously to the preparation of Example C-01, 3-bromo-4-oxo-piperidine-1-carboxylic acid tert-butyl ester is reacted with 2-imino-4-thiobiuret to form the title compound. tR 2.55 min (LC-1); ESI-MS (+): m/z 298.25 [M+H]+.

출처 및 근거

ORD 기록
ord-036640b60e664529845661e0ac98e940
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07727979B2

연결된 노트

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