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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 12074생성일: 2026년 10월 25일

Ethanol, 1-ethoxy-2,2,2-trifluoro- → 4-Trifluoromethyl-7-methyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

https://huagongshe.com/reaction/12074

반응식

참여 물질

역할이름HCID투입량
반응물Ethanol, 1-ethoxy-2,2,2-trifluoro-HCID 9897—
반응물4-Trifluoromethyl-7-methyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 9901266—
생성물4-Trifluoromethyl-7-methyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 10270119—

반응 단계

This compound was prepared in a similar fashion as that described in Example 84 from Compound 187 (Structure 33 of Scheme VI, where R1=methyl, n=1) and trifluoroacetaldehyde ethyl hemiacetal. 1H NMR (400 MHz, CDCl3) 11.08 (br. s, 1H), 7.06 (s, 1H), 7.00 (s, 1H), 6.99 (s, 1H), 3.99 (m, 1H), 3.81 (m, 1H), 3.67 (m, 1H), 3.10-2.95 (m, 1H), 2.92-2.82 (m, 1H), 2.07-1.97 (m, 1H), 1.93-1.80 (m, 1H), 1.19 (d, 3H, J=6.5).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07727980B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-98046a2630464160bd404d70de886952
출처 메모uspto-grants-2010_06