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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 12075생성일: 2026년 10월 25일

Ethanol, 1-ethoxy-2,2,2-trifluoro- → 4-Trifluoromethyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

https://huagongshe.com/reaction/12075

반응식

참여 물질

역할이름HCID투입량
반응물Ethanol, 1-ethoxy-2,2,2-trifluoro-HCID 9897—
반응물4-Trifluoromethyl-7-methyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 10270119—
생성물4-Trifluoromethyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 10154869—

반응 단계

This compound was prepared in a similar fashion as that described in Example 84 from Compound 192 (Structure 33 of Scheme VI, where R1═H, n=1) and trifluoroacetaldehyde ethyl hemiacetal. 1H NMR (400 MHz, CDCl3) 11.32 (br. s, 1H), 7.11 (s, 1H), 7.02 (s, 1H), 6.99 (s, 1H), 3.88 (q, 2H, J=8.9), 3.47 (t, 2H, J=5.6), 2.93 (t, 2H, J=6.3), 2.03 (m, 2H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07727980B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-2a6bbf7ff0534d48a19790d0a4deee4c
출처 메모uspto-grants-2010_06