4-(Trifluoromethoxy)phenylboronic acid → 6-(cyclopropylmethoxy)-N-(2-hydroxycyclohexyl)-5-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
반응식
[Br:1][c:2]1[c:3]([O:18][CH2:19][CH:20]2[CH2:21][CH2:22]2)[n:4][cH:5][c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH:11]([OH:16])[CH2:12][CH2:13][CH2:14][CH2:15]2)[cH:17]1.[F:23][C:24]([O:25][c:26]1[cH:27][cH:28][c:29]([B:32]([OH:33])[OH:34])[cH:30][cH:31]1)([F:35])[F:36]>>[c:2]1(-[c:29]2[cH:28][cH:27][c:26]([O:25][C:24]([F:23])([F:35])[F:36])[cH:31][cH:30]2)[c:3]([O:18][CH2:19][CH:20]2[CH2:21][CH2:22]2)[n:4][cH:5][c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH:11]([OH:16])[CH2:12][CH2:13][CH2:14][CH2:15]2)[cH:17]1참가 물질
3
출처 및 근거
- ORD 기록
- ord-d855c4c4b21d4c3b8a74e776c50acccc
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
반응 노트
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