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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 12078생성일: 2026년 10월 25일

Cyclopropanecarboxaldehyde → 4-Trifluoromethyl-6-cyclopropylmethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

https://huagongshe.com/reaction/12078

반응식

참여 물질

역할이름HCID투입량
반응물CyclopropanecarboxaldehydeHCID 123114—
반응물4-Trifluoromethyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 9835813—
생성물4-Trifluoromethyl-6-cyclopropylmethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 9945017—

반응 단계

This compound was prepared in a similar fashion as that described in Example 84 from Compound 192 (Structure 33 of Scheme VI, where R1═H, n=1) and cyclopropanecarboxaldehyde. 1H NMR (400 MHz, CDCl3) 11.44 (br. s, 1H), 7.06 (s, 1H), 7.00 (s, 1H), 6.92 (s, 1H), 3.40 (t, 2H, J=5.6), 3.21 (d, 2H, J=6.2), 2.90 (t, 2H, J=6.3), 1.99 (m, 2H), 1.07 (m, 1H), 0.58 (m, 2H), 0.27 (m, 2H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07727980B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-1bab2121c57e480fb6fea7acf1aeed55
출처 메모uspto-grants-2010_06