Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → 4-[(2-Chloro-6-methylpyrimidin-4-yl)oxy]-2,5-dimethylaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-Amino-2,5-dimethylphenol | HCID 76544 | — |
| 반응물 | 2,4-Dichloropyrimidine | HCID 77531 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-[(2-Chloro-6-methylpyrimidin-4-yl)oxy]-2,5-dimethylaniline | HCID 86628975 | — |
반응 단계
A solution of 4.53 g (33 mmol) 4-amino-2,5-dimethylphenol and 1.44 g NaOH (2M) in 30 ml water were added dropwise to a solution of 4.89 g (30.0 mmol) of 2,4-dichloropyrimidine in 50 ml of acetone. The reaction mixture was stirred for 20 h at ambient temperature.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727986B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-a317305e306944ef82b1ad5a3fc53986 |
| 출처 메모 | uspto-grants-2010_06 |