Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → 1-(3,5-Difluorophenyl)-2-methylpropan-2-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | 3,5-Difluorobenzyl bromide | HCID 518896 | — |
| 생성물 | 1-(3,5-Difluorophenyl)-2-methylpropan-2-ol | HCID 22063495 | — |
반응 단계
The target compound is obtained by reacting a Grignard compound, prepared from 25.0 g (121 mmol) of 3,5-difluorobenzyl bromide, with 12.6 mL (171 mmol) of acetone. Yellow oil. Yield: 13.5 g (60%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727984B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-f7612df1b54540428f756596601daa60 |
| 출처 메모 | uspto-grants-2010_06 |