Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(5-chloropyridin-2-yl)-5-methyl-2-nitrobenzamide → Chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(5-chloropyridin-2-yl)-5-methyl-2-nitrobenzamide | HCID 3562519 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Platinum | HCID 23939 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Chloride | HCID 312 | — |
| 생성물 | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | — |
반응 단계
To a solution of the compound of N-(5-chloro(2-pyridyl))(5-methyl-2-nitrophenyl)carboxamide (1.48 g, 5.1 mmol) in methanol (10 ml) was added 5% Pt/C (1.48 g, 0.19 mmol). The mixture was applied hydrogen balloon at r.t. for 2 hrs. After the filtration by Celite, the filtrate was concentrated to give (2-aminophenyl)-N-(2-pyridyl)carboxamide, C, chloride, N (1.36 g, 100%). MS found for C13H12ClN3O M+=262, (M+2)+=264.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727981B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-24b595b9283a44c19b23094563f6a21c |
| 출처 메모 | uspto-grants-2010_06 |