5-Amino-2-methylindole → {6-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-pyridin-2-yl}-(4-methyl-piperazin-1-yl)-methanone

반응식

[CH3:26][c:27]1[nH:28][c:29]2[cH:30][cH:31][c:32]([NH2:36])[cH:33][c:34]2[cH:35]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:11]1[cH:12][cH:13][cH:14][c:15]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][N:22]([CH3:25])[CH2:23][CH2:24]3)[n:16]1)[s:10]2>>[c:2]1([NH:36][c:32]2[cH:31][cH:30][c:29]3[nH:28][c:27]([CH3:26])[cH:35][c:34]3[cH:33]2)[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:11]1[cH:12][cH:13][cH:14][c:15]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][N:22]([CH3:25])[CH2:23][CH2:24]3)[n:16]1)[s:10]2

참가 물질

반응물 2

HCID 27339925-Amino-2-methylindole

HCID 18383088[6-(7-Chloro-thieno[3,2-b]pyridin-2-yl)-pyridin-2-yl]-(4-methyl-piperazin-1-yl)-methanone

생성물 1

HCID 18382758{6-[7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-pyridin-2-yl}-(4-methyl-piperazin-1-yl)-methanone

출처 및 근거

ORD 기록: ord-d1472fc29ea5485a999a40cfb9103649
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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