Dimethylformamide → 5-(6-Hydroxymethylpyridin-2-yl)-1-(4-methylpiperazin-1-yl)pent-4-yn-1-one

HRID 1216459

반응식

[Br:1][c:2]1[n:3][c:4]([CH2:8][OH:9])[cH:5][cH:6][cH:7]1.[C:23]([NH2:24])([CH3:25])([CH3:26])[CH3:27].[CH3:10][N:11]1[CH2:12][CH2:13][N:14]([C:17]([CH2:18][CH2:19][C:20]#[CH:21])=[O:22])[CH2:15][CH2:16]1.[Cu:28][I:29].[O:107]=[CH:108][N:109]([CH3:110])[CH3:111].[cH:30]1[cH:31][cH:32][c:33]([P:34]([Pd:35]([P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[P:74]([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[cH:105][cH:106]1>>[c:2]1([C:21]#[C:20][CH2:19][CH2:18][C:17]([N:14]2[CH2:13][CH2:12][N:11]([CH3:10])[CH2:16][CH2:15]2)=[O:22])[n:3][c:4]([CH2:8][OH:9])[cH:5][cH:6][cH:7]1