(Iodomethyl)cyclopentane → 4-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile

반응식

[Cl:1][c:2]1[cH:3][c:4]([OH:27])[c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH2:13][c:14]2[c:15]([F:22])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:23][cH:24][cH:25][cH:26]3)[cH:6][cH:7]1.[I:28][CH2:29][CH:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[Cl:1][c:2]1[cH:3][c:4]([O:27][CH2:29][CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34]2)[c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH2:13][c:14]2[c:15]([F:22])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:23][cH:24][cH:25][cH:26]3)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 2762531(Iodomethyl)cyclopentane

HCID 1363784754-[2-(4-Chloro-2-hydroxy-phenyl)-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile

생성물 1

HCID 670500034-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile

출처 및 근거

ORD 기록: ord-f405f706824c419bab7ac427a996f56b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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