Dichloromethane → 3-[2-(4-Amino-phenyl)-thiazol-4-yl]-1H-quinolin-2-one

HRID 1218369노트

반응식

HRID 1218369 반응식
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][cH:10][c:11](-[c:14]2[s:15][cH:16][c:17](-[c:19]3[c:20](=[O:29])[nH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[cH:28]3)[n:18]2)[cH:12][cH:13]1)([CH3:5])([CH3:6])[CH3:30].[Cl:31][CH2:32][Cl:33].[F:34][C:35]([F:36])([F:37])[C:38]([OH:39])=[O:40]>>[NH2:7][c:8]1[cH:9][cH:10][c:11](-[c:14]2[s:15][cH:16][c:17](-[c:19]3[c:20](=[O:29])[nH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[cH:28]3)[n:18]2)[cH:12][cH:13]1

참가 물질

4

반응물 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 58810140(4-[4-(2-Oxo-1,2-dihydro-quinolin-3-yl)-thiazol-2-yl]-phenyl)-carbamic acid tert-butyl ester

생성물 1

HCID 101497433-[2-(4-Amino-phenyl)-thiazol-4-yl]-1H-quinolin-2-one

출처 및 근거

ORD 기록
ord-ede69c131c6a4c9f8c211823003a3e4a
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

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