Dichloromethane → cis-4-amino-N-{[2-(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamide

반응식

[CH3:1][C:2]([N:5]([C:3](=[O:4])[O-:6])[CH:9]1[CH2:10][CH2:11][CH:12]([C:15](=[O:16])[NH:17][CH2:18][c:19]2[c:20]([C:25]([F:26])([F:27])[F:28])[cH:21][cH:22][cH:23][cH:24]2)[CH2:13][CH2:14]1)([CH3:7])[CH3:8].[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[NH2:5][CH:9]1[CH2:10][CH2:11][CH:12]([C:15](=[O:16])[NH:17][CH2:18][c:19]2[c:20]([C:25]([F:26])([F:27])[F:28])[cH:21][cH:22][cH:23][cH:24]2)[CH2:13][CH2:14]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 866400781,1-Dimethylethyl{cis-4-[({[2-(trifluoromethyl)phenyl]methyl}amino)carbonyl]cyclohexyl}carbamate

생성물 1

HCID 59242499cis-4-amino-N-{[2-(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamide

출처 및 근거

ORD 기록: ord-905c3f620ce34ef0a2b679d8dcdfa326
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…