6-(Methylcarbamoyl)pyridine-3-carboxylic acid → N5-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-N2-methylpyridine-2,5-dicarboxamide

반응식

[CH3:21][NH:22][C:23](=[O:24])[c:25]1[cH:26][cH:27][c:28]([C:31](=[O:32])[OH:33])[cH:29][n:30]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH2:20])[cH:11][n:12][c:13]2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH:20][C:31]([c:28]3[cH:27][cH:26][c:25]([C:23]([NH:22][CH3:21])=[O:24])[n:30][cH:29]3)=[O:32])[cH:11][n:12][c:13]2[O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:6][cH:7]1

참가 물질

반응물 2

HCID 151854186-(Methylcarbamoyl)pyridine-3-carboxylic acid

HCID 672813155-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine

생성물 1

HCID 67280399N5-(5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-N2-methylpyridine-2,5-dicarboxamide

출처 및 근거

ORD 기록: ord-61da531646384ee29f95002a842645ce
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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